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David E Kleiner Selected Research

Aspartate Aminotransferases (Aspartate Transaminase)

1/2021Hepatic Steatosis and Steatohepatitis in a Large North American Cohort of Adults With Chronic Hepatitis B.
1/2020Vibration-controlled transient elastography for the detection of cirrhosis in chronic hepatitis D infection.
1/2020Evaluating Noninvasive Markers to Identify Advanced Fibrosis by Liver Biopsy in HBV/HIV Co-infected Adults.
1/2020Hepatic Histology in Treatment-naïve Children With Chronic Hepatitis B Infection Living in the United States and Canada.
10/2019Association of Histologic Disease Activity With Progression of Nonalcoholic Fatty Liver Disease.
1/2018Among Patients With Nonalcoholic Fatty Liver Disease, Modest Alcohol Use Is Associated With Less Improvement in Histologic Steatosis and Steatohepatitis.
1/2018Relationship Between Metabolic Syndrome, Alanine Aminotransferase Levels, and Liver Disease Severity in a Multiethnic North American Cohort With Chronic Hepatitis B.
12/2016In Children With Nonalcoholic Fatty Liver Disease, Cysteamine Bitartrate Delayed Release Improves Liver Enzymes but Does Not Reduce Disease Activity Scores.
11/2013Clinical and histological determinants of nonalcoholic steatohepatitis and advanced fibrosis in elderly patients.
3/2013Discordance among transient elastography, aspartate aminotransferase to platelet ratio index, and histologic assessments of liver fibrosis in patients with chronic hepatitis C.
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David E Kleiner Research Topics

Disease

72Fibrosis (Cirrhosis)
05/2022 - 01/2003
50Non-alcoholic Fatty Liver Disease
10/2022 - 01/2004
37Inflammation (Inflammations)
11/2021 - 01/2003
32Liver Diseases (Liver Disease)
04/2022 - 01/2003
31Neoplasms (Cancer)
11/2022 - 05/2002
28Infections
04/2022 - 02/2003
21Chemical and Drug Induced Liver Injury
04/2022 - 06/2011
13Hepatocellular Carcinoma (Hepatoma)
12/2021 - 10/2010
13Chronic Hepatitis C
03/2015 - 02/2003
12Fatty Liver
10/2022 - 02/2005
10Insulin Resistance
01/2021 - 01/2004
9Disease Progression
11/2022 - 02/2003
9Hepatitis B
10/2022 - 10/2009
9Acute Liver Failure (Fulminant Hepatic Failure)
10/2021 - 06/2012
9Hepatitis
01/2021 - 08/2012
9Liver Cirrhosis (Hepatic Cirrhosis)
01/2021 - 01/2003
8Coinfection
10/2022 - 01/2013
8Hepatitis C
01/2020 - 02/2003
7HIV Infections (HIV Infection)
01/2021 - 03/2015
5Portal Hypertension
04/2022 - 10/2011
5Alcoholic Fatty Liver
01/2022 - 01/2009
5Hypertension (High Blood Pressure)
11/2021 - 08/2006
5Chronic Hepatitis B
01/2021 - 05/2009
5Body Weight (Weight, Body)
01/2021 - 04/2006
5Hypoxia (Hypoxemia)
10/2019 - 07/2006
4Metabolic Syndrome (Dysmetabolic Syndrome X)
01/2022 - 03/2011
4Autoimmune Hepatitis
01/2021 - 05/2009
4Necrosis
01/2018 - 01/2003
4Cholestasis
11/2017 - 01/2013
3Cholangiocarcinoma
12/2021 - 10/2010
3Hyperlipidemias (Hyperlipidemia)
11/2021 - 08/2014
3Hyperplasia
10/2021 - 07/2004
3Autoimmune Polyendocrinopathies (Schmidt Syndrome)
01/2021 - 08/2016
3COVID-19
01/2021 - 07/2020
3Melanoma (Melanoma, Malignant)
01/2019 - 08/2012
3Lipodystrophy
01/2017 - 04/2005
2Carcinoma (Carcinomatosis)
11/2022 - 01/2019
2Jaundice (Icterus)
04/2022 - 12/2017
2Weight Loss (Weight Reduction)
01/2022 - 01/2010
2Graft vs Host Disease (Graft-Versus-Host Disease)
01/2022 - 03/2017
2Liver Neoplasms (Liver Cancer)
12/2021 - 10/2010
2Colorectal Neoplasms (Colorectal Cancer)
10/2021 - 12/2019
2Chronic Hepatitis D
01/2021 - 10/2015

Drug/Important Bio-Agent (IBA)

23Alanine Transaminase (SGPT)IBA
11/2021 - 02/2004
19Biomarkers (Surrogate Marker)IBA
11/2022 - 01/2003
16RNA (Ribonucleic Acid)IBA
11/2022 - 07/2003
16Aspartate Aminotransferases (Aspartate Transaminase)IBA
01/2021 - 01/2003
12nasIBA
10/2022 - 06/2005
12Transaminases (Aminotransferases)IBA
04/2022 - 01/2003
11Pharmaceutical PreparationsIBA
01/2022 - 03/2007
10Dyphylline (Diprophylline)FDA Link
01/2022 - 06/2011
10EnzymesIBA
10/2021 - 11/2009
9DNA (Deoxyribonucleic Acid)IBA
05/2022 - 07/2004
8Triglycerides (Triacylglycerol)IBA
01/2022 - 04/2005
8Insulin (Novolin)FDA Link
01/2021 - 01/2004
8Antiviral Agents (Antivirals)IBA
01/2019 - 08/2006
7AntigensIBA
06/2022 - 07/2004
7Hepatitis B Surface Antigens (HBsAg)FDA Link
06/2022 - 10/2009
6Proteins (Proteins, Gene)FDA Link
01/2021 - 04/2009
6InterferonsIBA
01/2019 - 02/2003
6Pioglitazone (Actos)FDA Link
10/2015 - 01/2004
6Ribavirin (Virazole)FDA LinkGeneric
03/2015 - 07/2003
5Glucose (Dextrose)FDA LinkGeneric
01/2022 - 08/2014
5tesamorelinFDA Link
01/2021 - 12/2019
5AutoantibodiesIBA
01/2021 - 03/2009
5Vitamin EFDA LinkGeneric
10/2020 - 01/2009
5Alkaline PhosphataseIBA
11/2013 - 10/2006
4LipidsIBA
10/2022 - 07/2011
4Hepatitis B Core AntigensIBA
06/2022 - 10/2009
4Biological ProductsIBA
01/2021 - 07/2004
4Hepatitis B e AntigensIBA
01/2021 - 02/2015
4IronIBA
11/2017 - 02/2005
4LeptinIBA
01/2017 - 04/2005
4Alanine (L-Alanine)FDA Link
09/2010 - 01/2003
3Adrenal Cortex Hormones (Corticosteroids)IBA
04/2022 - 01/2017
3CytokinesIBA
11/2021 - 08/2006
3Growth Hormone-Releasing Hormone (Somatotropin Releasing Hormone)IBA
01/2021 - 01/2020
3Immunoglobulin G (IgG)IBA
11/2020 - 06/2008
3Protons (Proton)IBA
12/2019 - 01/2017
3Fatty Acids (Saturated Fatty Acids)IBA
03/2016 - 08/2006
2Oxaliplatin (Eloxatin)FDA LinkGeneric
11/2022 - 10/2021
2pembrolizumabIBA
11/2022 - 01/2019
2Lipoproteins (Lipoprotein)IBA
10/2022 - 01/2019
2Anticonvulsants (Antiepileptic Drugs)IBA
04/2022 - 01/2019
2TeaIBA
01/2022 - 01/2021
2Peptidoglycan (Murein)IBA
11/2021 - 07/2019
2Fluorouracil (Carac)FDA LinkGeneric
10/2021 - 12/2003
2LipopolysaccharidesIBA
01/2021 - 07/2019
2Cyclophosphamide (Cytoxan)FDA LinkGeneric
01/2021 - 12/2019
2Insulin-Like Growth Factor I (IGF-1)IBA
01/2021 - 07/2006

Therapy/Procedure

52Therapeutics
05/2022 - 02/2003
18Liver Transplantation
01/2022 - 02/2010
6Hematopoietic Stem Cell Transplantation
01/2022 - 03/2007
4Aftercare (After-Treatment)
12/2021 - 11/2006
4Bariatric Surgery
12/2021 - 12/2010
3Highly Active Antiretroviral Therapy (HAART)
01/2021 - 01/2013
3Transplantation
11/2019 - 01/2013
3Drug Therapy (Chemotherapy)
01/2017 - 12/2003
2Immunotherapy
12/2021 - 10/2010
2Adjuvant Chemotherapy
10/2021 - 10/2021